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Unable to start program- Access is denied in VS2010

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I am running Windows 7 as a local admin user.  I installed Visual Studio 2010 prof.  I upgraded from a Win xp 32 bit box to this x64 win 7 box.  I tried to start debugging on the WPF project I am working on and i can't start the debugger. I get the message "Error while trying to run project: Unable to start program '[path to the .exe] Access is denied.".  I get the same message when I try to start the project using release configuration as well.  

When I browsed to the application via \bin\debug and double click on the application I get an error "Windows cannot access the specified device, path or file. You may not have the appropriate permissions to access the item.  

I also get an access denied message while trying to install the click once application from this same project.  I think all of these problems are related.  I can't find any solutions on the web as of yet.  

I have given my user access to the entire root directory for this project.  This worked fine with VS 2010 on WinXP my old machine.

Please help.

thanks,

Rob


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