XBAP application went sometimes blank, after clear cache it works fine.

I hosted the XBAP application in windows server 2003 with 32bit environment

Development Environment :Visual Studio 2010 (windows 7 32 bit)

Its working fine. sometimes went blank screen that time refreshed several time no effect.

After clear cache it will working fine. I am not ask to clear cache each and every one user. What is the cause of issue. It will occurred randomly, it is not depends specific machine.

Please help me. Very urgent.

Note:

1.I kept "full trust mode" while publishing

2.Checked the option automatically increment the build version.