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Implementing relation between regions in prism and mvvm

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I want to design my new software with WPF, MVVM and PRISM. I have some done some project using WPF and MVVM so I’m familiar with them. Here is the structure of my ShellWindow.  

I want it work in the way that when I click on each option the workspace and the ribbons change accordingly so all three regions must be connected the problem is that I don’t know how to implement relation between my regions. And also when I click on a button on my ribbon how can I get information from for example a selected row on a gird in my workspace. I want to know how to use binding between my regions and completely using MVVM pattern and PRISM.


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